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Most people with dwarfism have a change in any of several specific genes that interfere with the normal development of cartilage and bones. All dwarfs are short, but different types of dwarfism have different causes and different physical traits.Since the longest bones in the human body are located in the arms and legs, this interference in normal bone development most commonly results in shorter limbs, which leads to short stature. Achondroplasia is the most common kind of dwarfism.People with diastrophic dwarfism have short calves and forearms and progressive curvature of the spine.They can have an inward- or downward-pointing foot (club foot) and differently positioned thumbs (sometimes called "hitchhiker thumbs").

Differences in the neck bones also can lead to spinal cord damage for some, if not monitored and treated appropriately.Some people may need to use crutches, a scooter, or a wheelchair to get around.Spondyloepiphyseal dysplasias are a group of rare genetic disorders that affect bone growth and can result in dwarfism. People with a particular kind of SED (specifically SED congenita) have a problem with the way a type of (type II collagen) assembles.Jeremy and Audrey have revealed their daughter will not be a dwarf as the gene is recessive and Audrey would have to have the same dwarfism running in her family tree, which she does not.Recent videos posted by the couple reveal that the TLC production crew is right there documenting every moment of the renovations.

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